Such patients have increased risk for cardiovascular disease. Impaired glucose tolerance is a quasi-entity 1% to 5% of such patients become overtly diabetic yearly. Some feel that it only determines glucose intolerance. The glucose tolerance test lacks specificity and sensitivity for the complications of diabetes mellitus. Diabetes is much more than glucose intolerance, but until now we have not been able to measure other factors pertinent to prediction of the complications of diabetes. Excessive growth hormone, adrenocortical and thyroid hormones, and catecholamines cause decreased glucose tolerance. Abnormal curves may be caused by Cushing's syndrome, pheochromocytoma, or acromegaly.Įmesis is probably an indication to cancel the remainder of a GGT for that day decision is up to the patient's physician. Glucose intolerance is due to obesity in some subjects. When a glucose level <50 mg/dL coincides with symptoms of hypoglycemia, a six-hour glucose tolerance test is advocated, 1 but many consider the alternative better. Risks of fetal abnormality and perinatal mortality are increased with abnormal carbohydrate metabolism in pregnancy.

It is used to predict perinatal morbidity in pregnancy, to diagnose gestational diabetes. The OGTT is used to work up glycosuria with- out hyperglycemia (eg, to work up renal glycosuria). Some use it in unexplained hypertriglyceridemia, neuropathy, impotence, diabetes-like renal diseases, retinopathy, reevaluation of prior diagnosis made under substandard conditions and with necrobiosis lipoidica diabeticorum. It is used in patients with borderline fasting and postprandial glucose to support or rule out the diagnosis of diabetes mellitus. The GTT only establishes the presence of glucose intolerance.

Two timing synonym